Your body manufactures it and cannot live without it. It facilitates more than 100 chemical reactions. Lack of it can cause depression, anxiety, impaired sense of balance, irritability, fatigue, deterioration of the immune system and ageing. It constantly needs replenishing, so a good supply of it does the body a power of good and is thought to slow down the process of ageing.
Many scientific studies have shown that Coenzyme-A (CoA) is the 'master enzyme' - in fact the most active metabolic enzyme in the body - that triggers so many metabolic processes. CoA is the vital catalyst needed to utilise Co-Q10, NADH and other energy producing metabolic enzymes. It is also thought to play a major role in the body's ability to cope with stress and strengthen the immune system.
CoA is the most active metabolic enzyme in the human body and is required to metabolise fat, carbohydrate and protein converting them into energy at the cellular level. One of the most crucial functions CoA performs is the initiation of the body's energy cycle (variously referred to as the ATP, TCA, Krebs or citric acid cycle), which produces over 90% of the body's energy.
Lack of CoA, or when the energy cycle is blocked, can cause a range of dysfunctions including fatigue, depression, anxiety, loss of appetite, impaired sense of balance, easy irritability and abnormal need for sleep. However, CoA is also vital to immune system support and the body's ability to cope with stress. All in all, it is a 'master' that is bound to generate a following.
Nicholaos Skouras, cell biologist and expert in Coenzyme A metabolism, made a significant breakthrough in the search to enhance levels of CoA in the human body. He created a unique product - Coenzyme A™ enabling the body to make more CoA itself within the cells, quite naturally.
Coenzyme A™ contains a balanced combination of active nutritional compounds that can be used by the body to support the manufacture and utilisation of this coenzyme.
Scientists at University of Miami have presented dramatic findings at a national cancer meeting that seem to show that Coenzyme Q10 can kill breast and prostate cancer cells. They believe CoQ10 could even be effectively applied as an ointment to the tumour sites.
CoQ10 is one of the most important antioxidants found in the body, and is used by cells not only to protect against free radical damage, but also to produce ATP.
High levels of CoQ10 are especially essential in the high activity cells, such as heart muscle cells, brain cells, and immune system cells. CoQ10 levels decrease with age, and lower levels have been observed in cancer, diabetes, and neurodegonerative diseases.
In laboratory and animal studies, the UM researchers found that by delivering CoQ10 to cancer cells and tissues, it induced apoptosis, the programmed cell death that goes awry in the disease process. "The most amazing part is that we've been able to restore a cancer cell's ability to kill itself, while not impacting normal cells", said research associate Niven Narain.
The scientists' first presentation involved the most common prostate cancer cell line, PC3. The researchers showed that adding CoQ10 to the cells in vitro, or in the laboratory, there was a 70% inhibition of cell growth over 48 hours and a reversal in the expression of a key anti-apoptotic protein.
In the second presentation, they showed the impact of CoQ10 on several different breast cancer cell lines. It greatly inhibited the proliferation of breast cancer cells, while stabilising normal mammary cells. This suggests to us that CoQ10 could be an effective adjuvant anti-tumour agent in breast carcinomas", they said.
The scientists have employed various ways to deliver the CoQ10, including through the skin. They used liposomes made of phospholipids as a molecular vehicle to deliver dermatologically active agents into targeted cells.
S.L. Hsia, PhD, director of the Transdermal Delivery/Cutaneous Biology Laboratory and principal investigator of the
research, said, "It is amazing that a benign compound, CoQ10, can cause the cancer cells to selectively kill themselves without harm to normal cells. Moreover, we have a novel topical delivery system that offers cancer patients an improved quality of life with a boost of energy. Indeed, our team looks forward to one day bringing the benefit and hope of this technology to many cancer patients."
Presented at the annual meeting of the American Association for Cancer Research, Anaheim, Ca, April 25 2005
Normal dosage:-
2 capsule with water 2 times per day

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